Control type | Positive tissue control High expression level | Positive tissue control Low expression levels | Negative tissue control |
---|---|---|---|
Tissue | Tonsil | Liver | Liver |
Description | All B- and T-cells must show a moderate to strong, distinct predominantly membranous staining reaction. | Virtually all Kupffer cells must show an at least weak to moderate predominantly membranous staining reaction.
Note lymphocytes will show strong staining reaction and cannot be used to evaluate analytical sensitivity. | No staining reaction in hepatocytes and epithelial cells of bile ducts. |
Example | All B- and T-cells must show a moderate to strong, distinct predominantly membranous staining reaction. | Virtually all Kupffer cells must show an at least weak to moderate predominantly membranous staining reaction.
Note lymphocytes will show strong staining reaction and cannot be used to evaluate analytical sensitivity. | No staining reaction in hepatocytes and epithelial cells of bile ducts. |